Covid | Concussion | Chemo

GLOBAL

Brain Fog

GLOBAL

To expand upon existing partnership network of leading centers across the US and Canada.

Brain Fog

Brain Fog

Brain Fog

The concept of subtle, insidious, changes in cognition are the silent brain health impairment that impacts everyone.

Solutions

Solutions

Solutions

To focus on objectively identifying, evaluating, and implementing successful and scalable treatment options.

Who matters in Global Brain Fog Solutions?

We all do. There is a rising interest and concern in subjective complaints around “brain fog.” However, subtle brain fog symptoms are rarely detectable, quantifiable, and most importantly, linked with possible pro-active treatments and therapies.

The vision of Global Brain Fog Solutions is to change this through evidence-based curation of clinical and technology innovations. Whether you are experiencing brain fog, caring for individuals who report it, or innovating potential evaluations and treatments, this initiative intends to coordinate a global response for us all.

Studies

Multiple studies will be conducted with the initial being Brain Fog Study 1 (BF1), the inaugural Global Brain Fog Solutions study begins Fall 2021. Future Brain Fog Studies are in planning to continue finding and curating innovative solutions.

2021

Mitigating Long-Term COVID-19 Consequences on Brain Health

Ryan C. N. D’Arcy, Jagdeep K. Sandhu, Shawn Marshall and Markus Besemann

COVID-19 is increasingly being linked to brain health impacts. The emerging situation is consistent with evidence of immunological injury to the brain, which has been described as a resulting “brain fog.” The situation need not be medicalized but rather clinically managed in terms of improving resilience for an over-stressed nervous system… 

Brain Vital Signs in Elite Ice Hockey: Towards Characterizing Objective and Specific Neurophysiological Reference Values for Concussion Management

Frederick R. Carrick, Guido Pagnacco, Sergio F. Azzolino4, Melissa Hunfalvay, Elena Oggero, Tory Frizzell, Christopher J. Smith7, Gabriela Pawlowski, Natasha K. J. Campbell, Shaun D. Fickling, Bimal Lakhani and Ryan C. N. D’Arcy

Prior concussion studies have shown that objective neurophysiological measures are sensitive to detecting concussive and subconcussive impairments in youth ice-hockey. These studies monitored brain vital signs at rink-side using a within-subjects design to demonstrate significant changes from pre-season baseline scans. However…

Subconcussive brain vital signs changes predict head-impact exposure in ice hockey players

Shaun D Fickling, Aynsley M Smith, Michael J Stuart, David W Dodick, Kyle Farrell, Sara C Pender, Ryan C N D’Arcy

The brain vital signs framework is a portable, objective, neurophysiological evaluation of brain function at point-of-care. We investigated brain vital signs at pre- and post-season for age 14 or under (Bantam) and age 16–20 (Junior-A) male ice hockey players to (i) further investigate previously published brain vital sign results showing subconcussive cognitive deficits…

2020

Brain Vital Signs in Elite Ice Hockey: Towards Characterizing Objective and Specific Neurophysiological Reference Values for Concussion Management

Frederick R. Carrick, Guido Pagnacco, Sergio F. Azzolino, Melissa Hunfalvay, Elena Oggero, Tory Frizzell, Christopher J. Smith7, Gabriela Pawlowski, Natasha K. J. Campbell, Shaun D. Fickling, Bimal Lakhani and Ryan C. N. D’Arcy

Prior concussion studies have shown that objective neurophysiological measures are sensitive to detecting concussive and subconcussive impairments in youth ice-hockey. These studies monitored brain vital signs at rink-side using a within-subjects design to demonstrate significant changes from pre-season baseline scans. However…

Innovations under evaluation:

Brain Health Research Institute (BHRI) - Brain Fog 1 Protocol

  • BHRI diet and nutrition guidelines
  • Cognitive fitness and rehabilitation
  • Physical fitness and rehabilitation
  • Sleep optimization
  • Mindfulness optimization

The NeuroCatch® Platform (NCP)

  • Objective cognitive evaluation
  • Quantified electroencephalography

BrainHQ Cognitive Fitness

  • Memory, attention, neuroplasticity
  • Tailored to individual performance

Translingual Neurostimulation (TNLS)

  • Portable Neuromodulation Stimulator (PoNS)
  • Physical and cognitive neuroplasticity

Cambridge Brain Sciences

  • Online neurocognitive testing platform
  • Higher-order cognitive components such as reasoning, memory, attention and verbal ability

Neuroreader® by Brainreader

  • MRI volumetric analysis
  • Functional MRI analysis

Magnetic Resonance Imaging (MRI)

  • High resolution anatomical imaging
  • Functional brain imaging

Biomarker Collection

  • Blood biomarkers
  • Saliva biomarkers

Media

People

Co-Lead:
Dr. Mary Kay Ross, MD,
Founder, Brain Health & Research Institute and CMO, Thorne Health Tech / Onegevity

Co-Lead:
Dr. Ryan D’Arcy, PhD, PIEng
President and Chief Scientific Officer, HealthTech Connex 

Dr. Michael Merzenich, PhD
Founder and CSO, BrainHQ

Dr. Henry Mahncke, PhD
CEOBrainHQ 

Dr. Leroy Hood, MD, PhD
Co-founder and Professor, Institute for Systems Biology

Dr. Nathan Price, PhD
CEO, Onegevity

Mads Fiig,
CEO of Brainreader

Rowena Rizzotti,
Co-Founder & Executive Lead, Legion Veterans Village

Dr. Jared Roach, MD, PhD
Senior Research Scientist, Institute for Systems Biology

Thom Mount
Strategic Advisor, Brain Health & Research Institute

Institute for Systems Biology

We are on a mission to make clinical research more efficient and accessible, to improve patient access to novel treatments for a positive impact on brain health.

The Centre for Neurology Studies is a clinical research site that provides professional consulting and study execution services to help our clients get their healthcare breakthroughs one step closer to market.

We serve diverse clients who range from brand new startups with “brainy” ideas but no idea where to start, to global medical device and pharmaceutical companies who need to complete their neurological phase III/IV clinical trials.

Partners

Healthtech Connex
Brainreader
Institute for Systems Biology
Brainreader
BrainHQ from Poist Science
Brainreader
Brainreader